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Hosein et al., 2012) didn’t display any toxicity profile related to renal dysfunction at dose-limiting toxicity (DLT)

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The compound has been found to operate in the postrema and nucleus of the hindbrain solitary tract in order to both induce satiety and regulate appetite by acting on receptors found in the laterodorsal tegmental nucleus, ventral tegmental area, and the hypothalamus [1]