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After activation, platelets in PRP can release a variety of growth factors, including transforming growth factor (TGF), platelet-derived growth factor (PDGF), insulin-like growth factor (IGF), basic fibroblast growth factors, vascular endothelial growth factor (VEGF), epidermal growth factors, and many others

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This lack of important data significantly limits the conclusions as to the actual efficacy of this therapeutic intervention