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MoCA, MMSE, the Modified Barthel Index (MBI), the Self-rating Depression Scale (SDS), Activities of Daily Living Scale (ADL), Hamilton Depression Rating Scale (HAMD), Hamilton Anxiety Rating Scale (HAMA), Pittsburgh Sleep Quality Index (PSQI), Loewenstein Occupational Therapy Cognition Assessment (LOTCA) and dementia quality of life questionnaire (DEMQOL) are the main tools for evaluating the efficacy of acupuncture

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Approximately 15-20% of the population carries genetic variants affecting copper homeostasis, potentially creating subgroups with enhanced or diminished peptide responsiveness