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In eukaryotes, GSH-Px enzymes catalyze the reduction of organic hydroperoxides and H 2 O 2 into their corresponding alcohols (or water, in the case of H 2 O 2 ) using GSH as an electron donor [15, 16]

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Thus, these two ASD-related synaptic proteins directly interact via SH3-binding domains and indirectly through binding to actin, determining the crosstalk between PMS and ADNP syndrome