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To comprehensively analyze existing evidence, we systematically searched PubMed and Web of Science using the following keyword combinations: ferroptosis AND (central nervous system injury)/ferroptosis AND (central nervous system damage)/ferroptosis AND (central nervous system disease)/ferroptosis AND (neurodegenerative diseases)/ferroptosis AND [(Parkinson’s disease) OR (Alzheimer’s disease) OR (Huntington’s disease) OR (multiple sclerosis)]/ferroptosis AND [(subarachnoid hemorrhage) OR (SAH)]/ferroptosis AND [(traumatic brain injury) OR TBI OR (head injury)]/ferroptosis AND [stroke OR (cerebral hemorrhage)]/ferroptosis AND (spinal cord injury)

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Melanin protects melanocytes and keratinocytes against H2O2-induced DNA strand breaks through its ability to bind Ca2+ Exp Cell Res